Pathophysiology of bacterial skin infections
The skin is thought to be a very effective barrier against invasion and subsequent bacterial illnesses, even though many different bacterial species come into touch with it or may be present there. The majority of situations where a person is predisposed to bacterial skin infections require a breach in the skin barrier; as a result, trauma like abrasion, excoriation, laceration, or ulceration may leave the skin exposed.
Furthermore, cutaneous infections are more likely to affect some ethnicities than others. Diabetes patients typically have inadequate blood flow (particularly to the hands and feet), and their leukocytes’ ability to fight infections is significantly reduced by high blood glucose levels. Patients who are old, have HIV/AIDS, or are receiving chemotherapy are also more at risk because of a weaker immune system.